A33V (p.Ala33Val) variant of TNFRSF1B (P20333)
A33V (p.Ala33Val) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
A33V (p.Ala33Val) variant details
- p.Ala33Val
- ExAC rs750041133
- TOPMed rs750041133
- gnomAD rs750041133
- Missense
- Variant Prioritization Score for Impact Estimate 0.141
- REVEL 0.10
- MetaLR 0.55
- MetaSVM -0.40
- CADD 0.84
- PolyPhen-2 0.00
- SIFT 0.40
- Most common in the African/African-American population (allele frequency 6e-05)
- Structural context available