A33T (p.Ala33Thr) variant of TNFRSF1B (P20333)
A33T (p.Ala33Thr) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
A33T (p.Ala33Thr) variant details
- p.Ala33Thr
- 1000Genomes rs540459773
- ExAC rs540459773
- TOPMed rs540459773
- gnomAD rs540459773
- Missense
- Variant Prioritization Score for Impact Estimate 0.131
- REVEL 0.08
- MetaLR 0.50
- MetaSVM -0.31
- CADD 0.99
- PolyPhen-2 0.00
- SIFT 0.53
- Most common in the 1KG:CDX population (allele frequency 0.0057)
- Structural context available