A33D (p.Ala33Asp) variant of TNFRSF1B (P20333)
A33D (p.Ala33Asp) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
A33D (p.Ala33Asp) variant details
- p.Ala33Asp
- gnomAD 1-12188815-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.192
- REVEL 0.20
- MetaLR 0.52
- MetaSVM -0.28
- CADD 1.17
- PolyPhen-2 0.10
- SIFT 0.22
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available