A2V (p.Ala2Val) variant of TNFRSF1B (P20333)
A2V (p.Ala2Val) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
A2V (p.Ala2Val) variant details
- p.Ala2Val
- gnomAD 1-12167096-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.306
- REVEL 0.21
- MetaLR 0.55
- MetaSVM -0.29
- CADD 18.90
- PolyPhen-2 0.04
- SIFT 0.16
- Population evidence available
- Structural context available
- Literature evidence available