A2S (p.Ala2Ser) variant of TNFRSF1B (P20333)
A2S (p.Ala2Ser) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
A2S (p.Ala2Ser) variant details
- p.Ala2Ser
- gnomAD 1-12167095-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.427
- REVEL 0.31
- MetaLR 0.74
- MetaSVM 0.07
- CADD 25.00
- PolyPhen-2 0.76
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available