A28T (p.Ala28Thr) variant of TNFRSF1B (P20333)
A28T (p.Ala28Thr) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
A28T (p.Ala28Thr) variant details
- p.Ala28Thr
- gnomAD 1-12188799-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.207
- REVEL 0.23
- MetaLR 0.52
- MetaSVM -0.36
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.61
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available