A28S (p.Ala28Ser) variant of TNFRSF1B (P20333)
A28S (p.Ala28Ser) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
A28S (p.Ala28Ser) variant details
- p.Ala28Ser
- Ensembl rs1570150813
- Missense
- Variant Prioritization Score for Impact Estimate 0.215
- REVEL 0.25
- MetaLR 0.57
- MetaSVM -0.33
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.54
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available