A25T (p.Ala25Thr) variant of TNFRSF1B (P20333)
A25T (p.Ala25Thr) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
A25T (p.Ala25Thr) variant details
- p.Ala25Thr
- gnomAD rs1382008273
- Missense
- Variant Prioritization Score for Impact Estimate 0.229
- REVEL 0.23
- MetaLR 0.54
- MetaSVM -0.42
- CADD 9.44
- PolyPhen-2 0.00
- SIFT 0.31
- Most common in the East Asian population (allele frequency 3.8e-05)
- Structural context available