A25S (p.Ala25Ser) variant of TNFRSF1B (P20333)
A25S (p.Ala25Ser) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
A25S (p.Ala25Ser) variant details
- p.Ala25Ser
- gnomAD 1-12167164-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.218
- REVEL 0.22
- MetaLR 0.53
- MetaSVM -0.38
- CADD 6.71
- PolyPhen-2 0.00
- SIFT 0.36
- Population evidence available
- Structural context available
- Literature evidence available