A25D (p.Ala25Asp) variant of TNFRSF1B (P20333)
A25D (p.Ala25Asp) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
A25D (p.Ala25Asp) variant details
- p.Ala25Asp
- gnomAD 1-12167165-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.452
- REVEL 0.51
- MetaLR 0.65
- MetaSVM -0.25
- CADD 18.60
- PolyPhen-2 0.02
- SIFT 0.12
- Population evidence available
- Structural context available
- Literature evidence available