A22V (p.Ala22Val) variant of TNFRSF1B (P20333)
A22V (p.Ala22Val) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
A22V (p.Ala22Val) variant details
- p.Ala22Val
- gnomAD 1-12167156-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.276
- REVEL 0.20
- MetaLR 0.64
- MetaSVM -0.28
- CADD 16.30
- PolyPhen-2 0.02
- SIFT 0.52
- Population evidence available
- Structural context available
- Literature evidence available