A22D (p.Ala22Asp) variant of TNFRSF1B (P20333)
A22D (p.Ala22Asp) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
A22D (p.Ala22Asp) variant details
- p.Ala22Asp
- gnomAD 1-12167156-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.362
- REVEL 0.38
- MetaLR 0.63
- MetaSVM -0.25
- CADD 15.90
- PolyPhen-2 0.05
- SIFT 0.15
- Population evidence available
- Structural context available
- Literature evidence available