A20T (p.Ala20Thr) variant of TNFRSF1B (P20333)
A20T (p.Ala20Thr) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
A20T (p.Ala20Thr) variant details
- p.Ala20Thr
- gnomAD 1-12167149-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.379
- REVEL 0.28
- MetaLR 0.58
- MetaSVM -0.17
- CADD 16.10
- PolyPhen-2 0.05
- SIFT 0.50
- Most common in the South Asian population (allele frequency 4.4e-05)
- Structural context available
- Literature evidence available