A20G (p.Ala20Gly) variant of TNFRSF1B (P20333)
A20G (p.Ala20Gly) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
A20G (p.Ala20Gly) variant details
- p.Ala20Gly
- gnomAD 1-12167150-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.289
- REVEL 0.22
- MetaLR 0.47
- MetaSVM -0.27
- CADD 9.35
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1e-06)
- Structural context available
- Literature evidence available