A19V (p.Ala19Val) variant of TNFRSF1B (P20333)
A19V (p.Ala19Val) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
A19V (p.Ala19Val) variant details
- p.Ala19Val
- gnomAD rs1421760930
- Missense
- Variant Prioritization Score for Impact Estimate 0.325
- REVEL 0.26
- MetaLR 0.58
- MetaSVM -0.18
- CADD 15.70
- PolyPhen-2 0.03
- SIFT 1.00
- Most common in the REMAINING population (allele frequency 2.1e-05)
- Structural context available