A18V (p.Ala18Val) variant of TNFRSF1B (P20333)
A18V (p.Ala18Val) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
A18V (p.Ala18Val) variant details
- p.Ala18Val
- gnomAD 1-12167144-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.27
- REVEL 0.19
- MetaLR 0.61
- MetaSVM -0.28
- CADD 15.40
- PolyPhen-2 0.08
- SIFT 0.25
- Most common in the Non-Finnish European population (allele frequency 2.1e-06)
- Structural context available
- Literature evidence available