A18S (p.Ala18Ser) variant of TNFRSF1B (P20333)
A18S (p.Ala18Ser) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
A18S (p.Ala18Ser) variant details
- p.Ala18Ser
- gnomAD 1-12167143-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.324
- REVEL 0.28
- MetaLR 0.62
- MetaSVM -0.20
- CADD 13.40
- PolyPhen-2 0.11
- SIFT 0.56
- Population evidence available
- Structural context available
- Literature evidence available