A18G (p.Ala18Gly) variant of TNFRSF1B (P20333)
A18G (p.Ala18Gly) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
A18G (p.Ala18Gly) variant details
- p.Ala18Gly
- gnomAD 1-12167144-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.268
- REVEL 0.19
- MetaLR 0.60
- MetaSVM -0.37
- CADD 15.40
- PolyPhen-2 0.00
- SIFT 0.54
- Most common in the Non-Finnish European population (allele frequency 1e-06)
- Structural context available
- Literature evidence available