A18D (p.Ala18Asp) variant of TNFRSF1B (P20333)
A18D (p.Ala18Asp) in TNFRSF1B (P20333) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
A18D (p.Ala18Asp) variant details
- p.Ala18Asp
- gnomAD 1-12167144-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.448
- REVEL 0.55
- MetaLR 0.63
- MetaSVM -0.28
- CADD 15.10
- PolyPhen-2 0.00
- SIFT 0.12
- Population evidence available
- Structural context available
- Literature evidence available