Y135H (p.Tyr135His) variant of TNFRSF1A (P19438)
Y135H (p.Tyr135His) in TNFRSF1A (P19438) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
Y135H (p.Tyr135His) variant details
- p.Tyr135His
- ExAC rs778922941
- gnomAD rs778922941
- Missense
- Variant Prioritization Score for Impact Estimate 0.258
- REVEL 0.35
- CADD 9.90
- PolyPhen-2 0.03
- SIFT 0.18
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available