T123I (p.Thr123Ile) variant of TNFRSF1A (P19438)
T123I (p.Thr123Ile) in TNFRSF1A (P19438) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data and structural context.
T123I (p.Thr123Ile) variant details
- p.Thr123Ile
- ExAC rs748101352
- gnomAD rs748101352
- Missense
- Variant Prioritization Score for Impact Estimate 0.788
- REVEL 0.92
- CADD 26.30
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available