L15V (p.Leu15Val) variant of TNFRSF1A (P19438)
L15V (p.Leu15Val) in TNFRSF1A (P19438) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
L15V (p.Leu15Val) variant details
- p.Leu15Val
- gnomAD rs1434421197
- Missense
- Variant Prioritization Score for Impact Estimate 0.497
- REVEL 0.61
- CADD 21.50
- PolyPhen-2 0.69
- SIFT 0.14
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available