G35R (p.Gly35Arg) variant of TNFRSF1A (P19438)
G35R (p.Gly35Arg) in TNFRSF1A (P19438) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
G35R (p.Gly35Arg) variant details
- p.Gly35Arg
- rs116336305
- 1000Genomes rs116336305
- ExAC rs116336305
- gnomAD rs116336305
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.335
- REVEL 0.47
- CADD 0.84
- PolyPhen-2 0.03
- SIFT 0.39
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the 1KG:YRI population (allele frequency 0.0043)
- Structural context available