D8E (p.Asp8Glu) variant of TNFRSF1A (P19438)
D8E (p.Asp8Glu) in TNFRSF1A (P19438) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
D8E (p.Asp8Glu) variant details
- p.Asp8Glu
- TOPMed rs1243050864
- Missense
- Variant Prioritization Score for Impact Estimate 0.498
- REVEL 0.50
- CADD 23.70
- PolyPhen-2 0.03
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available