S50G (p.Ser50Gly) variant of TNFRSF13C (Q96RJ3)
S50G (p.Ser50Gly) in TNFRSF13C (Q96RJ3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and published literature.
S50G (p.Ser50Gly) variant details
- p.Ser50Gly
- gnomAD 22-41926320-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.254
- REVEL 0.07
- MetaLR 0.05
- MetaSVM -1.07
- CADD 19.90
- PolyPhen-2 0.31
- SIFT 0.05
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Literature evidence available