S49G (p.Ser49Gly) variant of TNFRSF13C (Q96RJ3)
S49G (p.Ser49Gly) in TNFRSF13C (Q96RJ3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data.
S49G (p.Ser49Gly) variant details
- p.Ser49Gly
- 1000Genomes rs2146589499
- Missense
- Variant Prioritization Score for Impact Estimate 0.248
- REVEL 0.09
- CADD 21.90
- PolyPhen-2 0.31
- SIFT 0.01
- Most common in the HGDP:MAKRANI population (allele frequency 0.023)