P59S (p.Pro59Ser) variant of TNFRSF13C (Q96RJ3)
P59S (p.Pro59Ser) in TNFRSF13C (Q96RJ3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and published literature.
P59S (p.Pro59Ser) variant details
- p.Pro59Ser
- gnomAD 22-41926293-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.321
- REVEL 0.16
- MetaLR 0.12
- MetaSVM -0.87
- CADD 23.20
- PolyPhen-2 0.77
- SIFT 0.08
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Literature evidence available