Y39C (p.Tyr39Cys) variant of TNFRSF13B (O14836)
Y39C (p.Tyr39Cys) in TNFRSF13B (O14836) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
Y39C (p.Tyr39Cys) variant details
- p.Tyr39Cys
- gnomAD rs1395976297
- Missense
- Variant Prioritization Score for Impact Estimate 0.59
- REVEL 0.71
- CADD 25.00
- PolyPhen-2 0.93
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available