S70C (p.Ser70Cys) variant of TNFRSF13B (O14836)
S70C (p.Ser70Cys) in TNFRSF13B (O14836) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data.
S70C (p.Ser70Cys) variant details
- p.Ser70Cys
- gnomAD rs1390711436
- Missense
- Variant Prioritization Score for Impact Estimate 0.404
- REVEL 0.40
- CADD 23.00
- PolyPhen-2 0.80
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 0.00031)