S2G (p.Ser2Gly) variant of TNFRSF13B (O14836)
S2G (p.Ser2Gly) in TNFRSF13B (O14836) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data.
S2G (p.Ser2Gly) variant details
- p.Ser2Gly
- ExAC rs769586971
- gnomAD rs769586971
- Missense
- Variant Prioritization Score for Impact Estimate 0.297
- REVEL 0.28
- CADD 20.30
- PolyPhen-2 0.01
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)