P35T (p.Pro35Thr) variant of TNFRSF13B (O14836)
P35T (p.Pro35Thr) in TNFRSF13B (O14836) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data.
P35T (p.Pro35Thr) variant details
- p.Pro35Thr
- rs753500225
- ExAC rs753500225
- gnomAD rs753500225
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.427
- REVEL 0.43
- CADD 20.40
- PolyPhen-2 0.94
- SIFT 0.11
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the African/African-American population (allele frequency 4.8e-05)