E105K (p.Glu105Lys) variant of TNFRSF13B (O14836)
E105K (p.Glu105Lys) in TNFRSF13B (O14836) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
E105K (p.Glu105Lys) variant details
- p.Glu105Lys
- cosmic curated COSV10723
- ExAC rs768185098
- TOPMed rs768185098
- gnomAD rs768185098
- Missense
- Variant Prioritization Score for Impact Estimate 0.614
- REVEL 0.57
- CADD 25.00
- PolyPhen-2 0.91
- SIFT 0.03
- Most common in the HGDP:BURUSHO population (allele frequency 0.042)
- Structural context available