C47R (p.Cys47Arg) variant of TNFRSF13B (O14836)
C47R (p.Cys47Arg) in TNFRSF13B (O14836) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data and structural context.
C47R (p.Cys47Arg) variant details
- p.Cys47Arg
- ExAC rs769182186
- TOPMed rs769182186
- gnomAD rs769182186
- Missense
- Variant Prioritization Score for Impact Estimate 0.728
- REVEL 0.81
- CADD 23.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available