C104W (p.Cys104Trp) variant of TNFRSF13B (O14836)
C104W (p.Cys104Trp) in TNFRSF13B (O14836) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
C104W (p.Cys104Trp) variant details
- p.Cys104Trp
- TOPMed rs1486612247
- gnomAD rs1486612247
- Missense
- Variant Prioritization Score for Impact Estimate 0.583
- REVEL 0.83
- CADD 23.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available