C100Y (p.Cys100Tyr) variant of TNFRSF13B (O14836)
C100Y (p.Cys100Tyr) in TNFRSF13B (O14836) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
C100Y (p.Cys100Tyr) variant details
- p.Cys100Tyr
- 1000Genomes rs75885572
- ExAC rs75885572
- Missense
- Variant Prioritization Score for Impact Estimate 0.615
- REVEL 0.58
- CADD 23.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available