C100R (p.Cys100Arg) variant of TNFRSF13B (O14836)
C100R (p.Cys100Arg) in TNFRSF13B (O14836) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
C100R (p.Cys100Arg) variant details
- p.Cys100Arg
- TOPMed rs1364344942
- Missense
- Variant Prioritization Score for Impact Estimate 0.626
- REVEL 0.74
- CADD 24.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available