V19L (p.Val19Leu) variant of TNFAIP3 (P21580)
V19L (p.Val19Leu) in TNFAIP3 (P21580) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
V19L (p.Val19Leu) variant details
- p.Val19Leu
- Ensembl rs1776050169
- Missense
- Variant Prioritization Score for Impact Estimate 0.571
- MetaLR 0.03
- MetaSVM -1.09
- CADD 22.80
- PolyPhen-2 0.17
- SIFT 0.14
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available