R52S (p.Arg52Ser) variant of TNFAIP3 (P21580)
R52S (p.Arg52Ser) in TNFAIP3 (P21580) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
R52S (p.Arg52Ser) variant details
- p.Arg52Ser
- gnomAD rs1372271681
- Missense
- Variant Prioritization Score for Impact Estimate 0.519
- MetaLR 0.02
- MetaSVM -1.06
- CADD 22.30
- PolyPhen-2 0.56
- SIFT 0.44
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available