L10F (p.Leu10Phe) variant of TNFAIP3 (P21580)
L10F (p.Leu10Phe) in TNFAIP3 (P21580) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
L10F (p.Leu10Phe) variant details
- p.Leu10Phe
- Ensembl rs2114457728
- Missense
- Variant Prioritization Score for Impact Estimate 0.452
- MetaLR 0.11
- MetaSVM -0.94
- CADD 24.10
- PolyPhen-2 1.00
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available