K41E (p.Lys41Glu) variant of TNFAIP3 (P21580)
K41E (p.Lys41Glu) in TNFAIP3 (P21580) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
K41E (p.Lys41Glu) variant details
- p.Lys41Glu
- TOPMed rs1776053092
- Missense
- Variant Prioritization Score for Impact Estimate 0.472
- MetaLR 0.02
- MetaSVM -1.07
- CADD 22.90
- PolyPhen-2 0.00
- SIFT 0.15
- Most common in the Non-Finnish European population (allele frequency 2.1e-05)
- Structural context available