K20R (p.Lys20Arg) variant of TNFAIP3 (P21580)
K20R (p.Lys20Arg) in TNFAIP3 (P21580) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
K20R (p.Lys20Arg) variant details
- p.Lys20Arg
- 1000Genomes rs533720482
- ExAC rs533720482
- TOPMed rs533720482
- gnomAD rs533720482
- Missense
- Variant Prioritization Score for Impact Estimate 0.494
- MetaLR 0.04
- MetaSVM -1.11
- CADD 24.80
- PolyPhen-2 0.45
- SIFT 0.16
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available