I37T (p.Ile37Thr) variant of TNFAIP3 (P21580)
I37T (p.Ile37Thr) in TNFAIP3 (P21580) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, published literature, and structural context.
I37T (p.Ile37Thr) variant details
- p.Ile37Thr
- gnomAD 6-137871337-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.502
- CADD 27.60
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available