I36F (p.Ile36Phe) variant of TNFAIP3 (P21580)
I36F (p.Ile36Phe) in TNFAIP3 (P21580) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
I36F (p.Ile36Phe) variant details
- p.Ile36Phe
- ExAC rs770145346
- gnomAD rs770145346
- Missense
- Variant Prioritization Score for Impact Estimate 0.519
- AlphaMissense 0.29
- MetaLR 0.05
- MetaSVM -1.14
- CADD 26.40
- PolyPhen-2 0.98
- SIFT 0.09
- Most common in the South Asian population (allele frequency 4.6e-05)
- Structural context available