G35R (p.Gly35Arg) variant of TNFAIP3 (P21580)
G35R (p.Gly35Arg) in TNFAIP3 (P21580) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data, published literature, and structural context.
G35R (p.Gly35Arg) variant details
- p.Gly35Arg
- gnomAD 6-137871330-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.776
- CADD 25.30
- PolyPhen-2 0.98
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available