F51L (p.Phe51Leu) variant of TNFAIP3 (P21580)
F51L (p.Phe51Leu) in TNFAIP3 (P21580) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
F51L (p.Phe51Leu) variant details
- p.Phe51Leu
- TOPMed rs1776055571
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- MetaLR 0.02
- MetaSVM -1.07
- CADD 17.40
- PolyPhen-2 0.30
- SIFT 0.58
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available