F40C (p.Phe40Cys) variant of TNFAIP3 (P21580)
F40C (p.Phe40Cys) in TNFAIP3 (P21580) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
F40C (p.Phe40Cys) variant details
- p.Phe40Cys
- ExAC rs749663550
- gnomAD rs749663550
- Missense
- Variant Prioritization Score for Impact Estimate 0.529
- MetaLR 0.08
- MetaSVM -1.03
- CADD 29.40
- PolyPhen-2 0.73
- SIFT 0.05
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available