E27D (p.Glu27Asp) variant of TNFAIP3 (P21580)
E27D (p.Glu27Asp) in TNFAIP3 (P21580) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
E27D (p.Glu27Asp) variant details
- p.Glu27Asp
- ExAC rs778507437
- gnomAD rs778507437
- Missense
- Variant Prioritization Score for Impact Estimate 0.236
- MetaLR 0.02
- MetaSVM -1.02
- CADD 16.70
- PolyPhen-2 0.01
- SIFT 0.43
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available