C57F (p.Cys57Phe) variant of TNFAIP3 (P21580)
C57F (p.Cys57Phe) in TNFAIP3 (P21580) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data, published literature, and structural context.
C57F (p.Cys57Phe) variant details
- p.Cys57Phe
- gnomAD 6-137871397-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.598
- CADD 24.40
- PolyPhen-2 0.66
- SIFT 0.07
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available