C54F (p.Cys54Phe) variant of TNFAIP3 (P21580)
C54F (p.Cys54Phe) in TNFAIP3 (P21580) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
C54F (p.Cys54Phe) variant details
- p.Cys54Phe
- gnomAD rs1407911658
- Missense
- Variant Prioritization Score for Impact Estimate 0.617
- MetaLR 0.08
- MetaSVM -1.11
- CADD 27.70
- PolyPhen-2 0.86
- SIFT 0.05
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available