T83S (p.Thr83Ser) variant of TNF (Tumor necrosis factor)
T83S (p.Thr83Ser) in TNF (Tumor necrosis factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, published literature, and structural context.
T83S (p.Thr83Ser) variant details
- p.Thr83Ser
- gnomAD 6-31576781-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.178
- REVEL 0.21
- CADD 7.13
- PolyPhen-2 0.00
- SIFT 0.69
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available